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Clinical Trials | Research Study for Adults with Substance Use Disorder

Auricular Vagal Neuromodulation Therapy (AVNT) for the Alleviation of Depression and Anxiety in Substance Use Disorder

The University of Virginia’s Center for Neuromodulation Research is seeking adults ages 18-60 with substance use disorder who are currently receiving treatment for a research study. The purpose of this study is to learn whether a non-invasive ear device may help improve mood, anxiety, sleep, and cravings in people with substance use disorder. Study participation lasts about 30 days and includes 5 in-person study visits. Participants will be asked to use a study device at home for about 60 minutes each day, complete questionnaires about mood, anxiety, sleep, and substance use, participate in brief computer-based activities, and complete short daily surveys using a smartphone application. Study-related visits, assessments, and use of the study device are provided at no cost. Participation is voluntary. For more information, contact: [email protected] 434-924-2097 Interested individuals may also complete a brief online pre-screening questionnaire to determine whether they may qualify for the study: